This method is for the determination of 4,4'-methylenedianiline (MDA). The sample is collected on an acid-treated glass fiber filter. After collection the filter is extracted with 0.1 N KOH in methanol and analyzed by HPLC with UV and electrochemical detection.
4,4-Diphenylmethane diisocyanate (MDI) is a known interference with this method as it will convert to MDA once collected on the acid treated filter.
The working range of the method is 0.025 ppb to 1.2 ppm (0.0002 to 10 mg/m3) for a 100-L air sample and the method is applicable to STEL (short term exposure limit) measurements.
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| Hold Times, Preservatives, Preps, Collection, Analytical & Documentation | |
|---|---|
| Holding Time: | The filter is stable at least 60 days if kept at 20 °C. |
| Preservatives: | Store the sample at 20°C. |
| Required Preps: | 37mm Sulfuric acid treated glass fiber filter (SKC 225-9004) |
| Collection Method: | The method recommends a 1-2 L/min. flow rate with a 10L to 1000L sample collection volume. |
| Analytical Methodology: | HPLC/UV |
| Documentation: | 
5029
|
| Analyte | Formula | CAS Number | Detection Limit | |
|---|---|---|---|---|
| 4,4'-Methylenedianiline | C13H14N2 |
101-77-9 |
0.2 |
µg |
* The analytes and detection limits listed for each method represent the typical detection limits and analytes reported for that particular method. Keep in mind that analyte lists may vary from laboratory to laboratory. Detection limits may also vary from lab to lab and are dependent upon the sample size, matrix, and any interferences that may be present in the sample.